Murgaon Education Society was established in 1971 with the noble goal of providing educational facilities at Vasco-da-Gama and in other parts of Murgao Taluka by developing professional skills among its students, and by providing a select core of leadership qualities. The College has become, over the years, a positive force for national and global development. The first educational institution set up by the Murgao Education Society was the college of Arts and Commerce, which was established at Vasco-da-Gama in 1972. This was also the first composite Arts and Commerce College in the State of Goa to be affiliated to the University of Mumbai and then to the Goa University. The College seeks to bring about an all round integrated development of the intellectual, moral and physical faculties of its students, so that they can become self reliant, play a positive role in the nation building and provide leadership to the society in various walks of life. Pursuit of excellence is the motto of the College. The College was shifted to its present Zuarinagar Campus in June 1985.

In recognition of the high standards of education and an all round excellence attained by it, the College has been selected by the University Grants Commission for introducing vocational courses at the BA and B.Com degree level and by the Ford Foundation, U.S.A. for implementing its Campus Diversity Initiative Programmes. The pursuit of excellence has fetched one more feather to the crown of glory of the M.E.S. College. The College was granted re-accreditation by the National Assessment and Accreditation Council (NAAC) of the University Grants Commission with B++ in the year 2006. Further, the UGC has selected the institution to introduce the ‘B.Com in Shipping Management’ Course under its innovative programme. Also, the UGC has chosen the college to introduce a career oriented course entitled, ‘Management of NGO’s’.